An Update on the Biology and the Therapy of Chronic Lymphocytic Leukemia (CLL)
22. May – 23. May 2025, Hotel Gersbergalm, Salzburg
The Cancer Cluster Salzburg (CCS) meeting will be held jointly with our annual workshop on chronic lymphocytic leukemia “An Update on the Biology and the Therapy of Chronic Lymphocytic Leukemia (CLL)“ and provides a stimulating forum to share and discuss exciting and novel data. Both workshops will be held on May 22nd – May 23rd 2025 as a physical Meeting. The conference will provide an update on the most recent insights into basic and clinical aspects of cancer.
We are confident that this workshop with a very ambitious scientific program will be most memorable to you.
In order of appearanceThe Faculty
Prof. Richard Greil MD
Head of Austrian Group for Medical Tumor Therapy (AGMT) GmbH, Salzburg Cancer Research Institute-Laboratory for Immunological an Molecular Cancer Research (SCRI-LIMCR), Cancer Cluster Salzburg (CCS), Salzburg, Austria Prof. Dr. Fritz Aberger
Molecular Cancer and Stem Cell Research, Lab Department of Molecular Biology, University of Salzburg, Cancer Cluster Salzburg (CCS), Salzburg, Austria Dr. Spencer Watson
Senior Research Fellow at CHUV University Hospital Lausanne, Lausanne, Switzerland Prof. Davor Lessel MD PhD Full Professor of Human Genetics and Director of Institute of Human Genetics, University of Regensburg, and Institute of Clinical Human Genetics, University Hospital Regensburg, Regensburg, Germany Adrian Wiestner MD PhD
Head of Laboratory of Lymphoid Malignancies, Hematology Branch, National Institutes of Health (NIH), Bethesda, USA Prof. Binyamin Knisbacher PhD
Assistant Professor at Bar-Ilan University, Bioinformatics and Microarray Unit, Ramat Gan, Israel Dr. Maike Buchner Junior Group Leader at Technical University of Munich, Munich, Germany Prof. Ingo Ringshausen MD
Associate Professor in Haemato Oncology, University of Cambridge, Cambridge and University College London Hospitals NHS Foundation Trust, London, UK Talha Munir MBChB PhD
Consultant hematologist at Leeds Teaching Hospitals NHS Trust and deputy chair of United Kingdom (UK) National Cancer Research Institute (NCRI) Chronic Lymphocytic Leukemia (CLL) Study Group, Leeds, UK Prof. Marek Mráz PhD Research Group Leader Senior at CEITEC – Central European Institute of Technology, Brno, Czech Republic Prof. Michael Schmitt MD MHBA Siebeneicher-Stiftungsprofessor for Cellular Immunotherapy at the University of Heidelberg, Head of the Good Manufacturing Practice (GMP) Core Facility, Head of the Cellular Immunotherapy Working Group, Heidelberg University Hospital, Heidelberg, Germany Christoph Schultheiss PhD
Project Leader, Departement Biomedizin, DBM Hebelstrasse – FG Binder, University Hospital of Basel, Basel, Switzerland Prof. Clemens Wendtner MD
Senior Consultant for Haematology/Oncology and Infectiology at the Ludwig-Maximilians-University (LMU), Head of Oncology at the Interdisciplinary Oncology Centre (IOZ), Munich, Germany Prof. Dimitar Efremov MD PhD Group leader, Molecular Hematology International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy Prof. Julien Broséus MD Associate Professor, Université de Lorraine, Nancy, France Riccardo Moia MD PhD Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy Othman Al-Sawaf MD Haematologist and medical oncologist at Clinic I for Internal Medicine at Cologne University Hospital, Cologne, Germany
preliminaryProgramme
CCS Workshop | Thursday, 22. May 2025
13:00 – 13:10 Welcome & Introduction
Richard Greil and Fritz Aberger (Salzburg)
13:10 – 13:40 Detailed programme coming soon!
14:10 – 14:30 Coffee Break
14:30 – 15:30 Detailed programme coming soon!
15:30 – 15:45 Closing Remarks
Richard Greil and Fritz Aberger (Salzburg)
15:45 – 17:00 Coffee Break & Poster Session
CLL Workshop | Thursday, 22. May 2025
17:00 – 18:10 Keynote Lecture CLL
Adrian Wiestner (Bethesda, USA)
18:30 Come Together
19:00 Networking Dinner
CLL Workshop | Friday, 23. May 2025
08:15 – 08:30 Welcome & Introduction Richard Greil (Salzburg)
08:30 – 10:30 Immune Dysregulation and Therapeutic Options
CLL Subgroups and Treatment Strategies* Binyamin Knisbacher (Israel)
Signaling Homeostasis in CLL through Balanced Activation and Feedback Control* Maike Buchner (Munich)
Dissecting TME-interactions in CLL* Ingo Ringshausen (Cambridge)
Future of Combination Treatment*
Talha Munir (Leeds)
*Discussion after lecture
10:30 – 11:00 Coffee break
11:00 – 13:00 Immunotherapy Approaches B-T cell Interactions in CLL and FL* Marek Mraz (Brno)
3rd Gen CAR-T* Michael Schmitt (Heidelberg)
IGLV-specific CAR-T* Christoph Schultheiss (Basel)
Clinical Immunotherapy* Clemens Wendtner (Munich) *Discussion after lecture
13:00 – 14:00 Business Lunch
14:00 – 16:00 Richter Syndrome Dissecting the Interplay between Genetic Lesions and the Tumor Microenvironment in Richter Syndrome* Efremov Dimitar (Trieste)
DNA Methylation and Gene Expression Profiles in Richter Transformation : Looking for CLL Imprint and Extending to de novo DLBCLs* Julien Broséus (Lorraine, Ulm)
Clonal Hematopoiesis in CLL and Richter Transformation* Riccardo Moia (Novara)
Clinical Therapy* Othman Al-Sawaf (Cologne) *Discussion after lecture
16:00 – 16:15 Closing Remarks Richard Greil (Salzburg)
Registration
The registration form will be available soon, we look forward to your submission. We would like to point out that this conference is not open to the public. After your registration your entries will be checked by us, followed by information about your requested participation.
Accreditation by ÖÄK
For the 19th International CLL Workshop 2025 10 DFP points are requested at the Diploma Continuing Education Programme of the Austrian Medical Association (ÖÄK).
The hotel can be reached by car (sufficient parking available), by bus (line 151) or by cab (still city area). A shuttle will be organised between Salzburg Central Station and Venue.
Scientific Organising Committee
Univ. Prof. Dr. Richard Greil, Salzburg
PD Dr. Nadja Zaborsky, Salzburg
PD. Dr. Roland Geisberger, Salzburg
ao. Univ. Prof. Dr. Alexander Egle, Salzburg Laboratory for Immunological and Molecular Cancer Research Cancer Cluster Salzburg Third Medical Department with Hematology, Oncology, Hemostaseology, Infectiology and Rheumatology, Paracelsus Medical University, Salzburg, Austria
in cooperation with
Prof. Dr. Fritz Aberger Department Biosciences, Paris-Lodron University Salzburg
Cancer Cluster Salzburg | www.cancercluster-salzburg.at
Organisation Institution
Univ. Prof. Dr. Richard Greil, Salzburg AGMT gemeinnützige GmbH Gentzgasse 60/21 1180 Wien Austria
Contact: Mag. Matthias Florian | m.florian@agmt.at
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